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Welcome to the UAB Department of Pathology website. The UAB Department of Pathology provides extensive clinical services and teaching while maintaining large and productive research programs. Currently, the Department has over $20 million per year in extramural research funding and our clinical services, including inpatient, outpatient and outreach, completes over 6 million procedures per year. Our training programs are among the finest in the country and our faculty have achieved national and international recognition in service, teaching and research.
UAB Pathology News
21st Annual Paulette Shirey Pritchett Lecture
June 15, 2012 - 2:00 p.m. Margaret Cameron Spain Auditorium
Sir Salvador Moncada, M.D., Ph.D, D.Sc.
Professor of Experimental Biology and Therapeutics
Wolfson Institute for Biomedical Research
University College London
This endowed lecture series is named in honor of Dr. Paulette Shirey Pritchett. Dr. Pritchett was a highly respected, young member of the UAB Department of Pathology when she unexpectedly passed away on August 4, 1984. It is widely recognized as the premier named lectureship at UAB in Experimental Pathology and previous recipients have included several Nobel Laureates and Academy Members.
This year we are pleased to honor Professor Sir Salvador Moncada as the 2012 lecturer. Dr. Moncada obtained his M.D. at the University of El Salvador and his Ph.D. from the University of London, where he contributed to the discovery that aspirin-like drugs inhibit prostaglandin biosynthesis, thus accounting for their analgesic, anti-pyretic and anti-inflammatory actions. In 1975 he joined the Wellcome Research Laboratories where he initiated the work leading to the discovery of the enzyme thromboxane synthase and the vasodilator prostacyclin. This work contributed to the understanding of how low doses of aspirin prevent cardiovascular episodes such as myocardial infarction and stroke. He was also responsible for the identification of nitric oxide as a biological mediator and the elucidation of the metabolic pathway leading to its synthesis. A great deal of the early work on the biological significance of nitric oxide in the cardiovascular system came from his laboratory as well as some fundamental information about the role of nitric oxide in the peripheral and central nervous system and in cancer. In 1996 Prof. Moncada moved to University College London to establish and direct the Wolfson Institute for Biomedical Research. He has continued his research more recently in the areas of mitochondrial biology and cell metabolism where he has made significant contributions. In the last two years, his work has led to the discovery of the molecular mechanism responsible for the coordination between cell proliferation and the provision of the metabolic substrates required for this process. Professor Moncada is a Fellow of the Royal Society and a Foreign Associate of the National Academy of Science of the USA and in 2010 he received a Knighthood for his services to Science.
We thank Dr. Pritchett and members of his family for making this lectureship possible.
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